Koronavirus berkaitan sindrom pernapasan akut berat

Koronavirus berkaitan sindrom pernapasan akut berat (SARSr-CoV atau SARS-CoV)[note 1] adalah spesies koronavirus yang menjangkiti manusia, kelelawar, dan beberapa mamalia tertentu.[2][3] Virus ini adalah virus RNA beruntai tunggal sense positif berselubung yang memasuki sel inangnya dengan mengikat reseptor enzim pengubah angiotensin 2 (ACE2).[4] Virus ini adalah anggota genus Betacoronavirus dan subgenus Sarbecovirus.[5][6]

Koronavirus berkaitan sindrom pernapasan akut berat
SARS-CoV with corona.jpg
Mikrograf elektron transmisi dari koronavirus berkaitan SARS yang muncul dari sel inang yang dikultur di laboratorium
Klasifikasi virus e
Takson tak dikenal (fix): Sarbecovirus
Spesies:
Koronavirus berkaitan sindrom pernapasan akut berat
Galur
Sinonim
  • Koronavirus SARS
  • Koronavirus berkaitan SARS-related coronavirus
  • Koronavirus sindrom pernapasan akut berat[1]

Dua galur virus ini telah menyebabkan wabah penyakit pernapasan parah pada manusia, yaitu koronavirus sindrom pernapasan akut berat (SARS-CoV atau SARS-CoV-1), yang menyebabkan wabah sindrom pernapasan akut berat (SARS) pada 2002–2004, dan koronavirus sindrom pernapasan akut berat 2 (SARS-CoV-2), yang menyebabkan pandemi terkini penyakit koronavirus 2019 (COVID-19).[7][8] Terdapat ratusan galur SARS-CoV lainnya, yang semuanya hanya diketahui menjangkiti spesies bukan manusia, yaitu bats are a major reservoir of many strains of SARS-related coronaviruses, and several strains have been identified in palm civets, which were likely ancestors of SARS-CoV.[7][9]

Lihat pulaSunting

CatatanSunting

  1. ^ The terms SARSr-CoV and SARS-CoV are sometimes used interchangeably, especially prior to the discovery of SARS-CoV-2.

ReferensiSunting

  1. ^ "ICTV Taxonomy history: Severe acute respiratory syndrome-related coronavirus". International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggris). Diakses tanggal 27 January 2019. 
  2. ^ Branswell H (9 November 2015). "SARS-like virus in bats shows potential to infect humans, study finds". Stat News. Diakses tanggal 20 February 2020. 
  3. ^ Wong AC, Li X, Lau SK, Woo PC (February 2019). "Global Epidemiology of Bat Coronaviruses". Viruses. 11 (2): 174. doi:10.3390/v11020174. PMC 6409556 . PMID 30791586. Most notably, horseshoe bats were found to be the reservoir of SARS-like CoVs, while palm civet cats are considered to be the intermediate host for SARS-CoVs [43,44,45]. 
  4. ^ Kesalahan pengutipan: Tag <ref> tidak sah; tidak ditemukan teks untuk ref bernama pmid24172901
  5. ^ "Virus Taxonomy: 2018 Release". International Committee on Taxonomy of Viruses (ICTV) (dalam bahasa Inggris). October 2018. Diakses tanggal 13 January 2019. 
  6. ^ Woo PC, Huang Y, Lau SK, Yuen KY (August 2010). "Coronavirus genomics and bioinformatics analysis". Viruses. 2 (8): 1804–20. doi:10.3390/v2081803. PMC 3185738 . PMID 21994708. Figure 2. Phylogenetic analysis of RNA-dependent RNA polymerases (Pol) of coronaviruses with complete genome sequences available. The tree was constructed by the neighbor-joining method and rooted using Breda virus polyprotein. 
  7. ^ a b Coronaviridae Study Group of the International Committee on Taxonomy of Viruses (March 2020). "The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2". Nature Microbiology. 5 (4): 536–544. doi:10.1038/s41564-020-0695-z . PMC 7095448 . PMID 32123347. 
  8. ^ Kohen, Jon; Kupferschmidth, Kai (28 February 2020). "Strategies shift as coronavirus pandemic looms". Science. 367 (6481): 962–963. Bibcode:2020Sci...367..962C. doi:10.1126/science.367.6481.962 . PMID 32108093. 
  9. ^ Lau SK, Li KS, Huang Y, Shek CT, Tse H, Wang M, et al. (March 2010). "Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events". Journal of Virology. 84 (6): 2808–19. doi:10.1128/JVI.02219-09 . PMC 2826035 . PMID 20071579. 

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Templat:SARS