Faktor stimulasi koloni granulosit

CSF3
Struktur yang tersedia
PDB	Pencarian Ortolog: PDBe RCSB
Daftar kode id PDB
	2D9Q, 1CD9, 1GNC, 1PGR, 1RHG
Pengidentifikasi
Alias	CSF3, C17orf33, CSF3OS, GCSF, colony stimulating factor 3
ID eksternal	OMIM: 138970 MGI: 1339751 HomoloGene: 7677 GeneCards: CSF3
Lokasi gen (Tikus)
Kr.	Kromosom 11 (tikus)
Akhir	98,594,455 bp
Pola ekspresi RNA
	Referensi data ekspresi selengkapnya
Ontologi gen
Fungsi molekuler	• cytokine activity; • enzyme binding; • growth factor activity; • granulocyte colony-stimulating factor receptor binding;
Komponen seluler	• extracellular region; • extracellular space;
Proses biologis	• positive regulation of protein kinase B signaling; • positive regulation of actin filament polymerization; • cellular response to cytokine stimulus; • positive regulation of peptidyl-serine phosphorylation; • multicellular organism development; • granulocyte differentiation; • GO:0046730, GO:0046737, GO:0046738, GO:0046736 respons imun; • positive regulation of peptidyl-tyrosine phosphorylation; • positive regulation of phosphatidylinositol 3-kinase signaling; • positive regulation of protein binding; • cellular response to lipopolysaccharide; • positive regulation of actin cytoskeleton reorganization; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • negative regulation of neuron death; • positive regulation of myeloid cell differentiation; • response to ethanol; • positive regulation of cell population proliferation; • neutrophil differentiation; • macrophage differentiation; • myeloid cell development; • regulation of signaling receptor activity; • cytokine-mediated signaling pathway; • positive regulation of DNA-binding transcription factor activity;
	Sumber:Amigo / QuickGO
Ortolog
	1440
	12985
	ENSG00000108342
	ENSMUSG00000038067
	P09919
	P09920
	NM_000759; NM_001178147; NM_172219; NM_172220
	NM_009971
	NP_000750; NP_001171618; NP_757373; NP_757374
	NP_034101
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

Faktor stimulasi koloni granulosit (bahasa Inggris: Granulocyte colony-stimulating factor, colony-stimulating factor 3, G-CSF, CSF-3) adalah hormon berupa glikoprotein dengan fungsi faktor pertumbuhan, mitogen, sitokina, yang disekresi oleh berbagai jaringan untuk menstimulasi sumsum tulang agar mensintesis granulosit dan sel punca dan melepaskannya ke dalam peredaran darah.

Rujukan

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000038067 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

Artikel bertopik biokimia ini adalah sebuah rintisan. Anda dapat membantu Wikipedia dengan mengembangkannya.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000038067 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

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