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The nucleus paragigantocellularis of the brain has been identified as involved in ejaculatory control.<ref>{{cite journal |author=Coolen LM, Olivier B, Peters HJ, Veening JG|title=Demonstration of ejaculation-induced neural activity in the male rat brain using 5-HT1A agonist 8-OH-DPAT |journal=Physiol. Behav. |volume=62 |issue=4 |pages=881–91 |year=1997|pmid=9284512 |doi=10.1016/S0031-9384(97)00258-8}}</ref> Scientists have long suspected a [[genetics|genetic]] link to certain forms of premature ejaculation. In one study, 91 percent of men who have had premature ejaculation for their entire lives also had a first-relative with lifelong premature ejaculation. Other researchers have noted that men who have premature ejaculation have a faster neurological response in the pelvic muscles.{{citation needed|date=April 2013}}
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[http://www.obatejakulasidinialami.net Ejakulasi dini] dapat terjadi karena [[radang prostat]]<ref name=Althof2010>{{cite journal |author= Althof, S.E. et al. |title= International Society for Sexual Medicine’s Guidelines for the Diagnosis and Treatment of Premature Ejaculation |journal= Journal of Sexual Medicine|volume=7|page=2947|year=2010|pmid=21050394 |doi=10.1111/j.1743-6109.2010.01975.x |issue=9}}</ref> atau efek samping dari obat-obatan.
 
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