[[Berkas:Rebecca_Ferguson_at_the_Mission_Impossible_–_Rogue_Nation_Global_Premiere_in_ViennaRebecca Ferguson at the Mission Impossible – Rogue Nation Global Premiere in Vienna,_Austria Austria.jpg|jmpl|Rebecca Ferguson bersama Steven Gätjen dalam global premier the Mission: Impossible – Rogue Nation di Vienna, Austria.]]
Dia mulai menarik perhatian dengan perannya yang menonjol sebagai seorang gadis kelas-atas Anna Gripenhielm dalam opera sabun ''Nya tider''. Kemudian dia melanjutkan untuk bermain sebagai Chrissy dalam opera sabun Swedia-Amerika ''Ocean Ave.''
Sutradara Swedia Richard Hobert menemukannya di pasar kota Simrishamn pada tahun 2011, dan mengajaknya membintangi film ''A One – Way to Antibes''.<ref>{{Cite web|url=http://sverigesradio.se/sida/artikel.aspx?programid=2785&artikel=4717289|title=Rebecca Ferguson hälsade på! - P3 Populär|date=2011-09-27|publisher=Sverigesradio.se|author=Rebecca Ferguson och Tara fixar hårsvallen!|accessdate=2012-10-20}}</ref> Dia juga muncul dalam film horor ''Strandvaskaren'' dan film ''Vi'' pada tahun 2012 bersama dengan Gustaf Skarsgård.<ref>{{Cite web|url=http://actorsinscandinavia.com/actors/rebecca-ferguson/|title=Rebecca Ferguson|date=|publisher=Actors in Scandinavia|accessdate=2012-09-07}}</ref><ref>{{Cite web|url=http://www.aftonbladet.se/nojesbladet/article14951798.ab|title=Skarsgård jobbar helt naken – gratis | Nöjesbladet | Aftonbladet|date=2012-06-09|publisher=Aftonbladet.se|accessdate=2012-09-07}}</ref>
Pada bulan Agustus 2012, Ferguson dikabarkan terpilih untuk memerankan Elizabeth Woodville dalam drama sejarah sepuluh babak di [[BBC|BBC,]], ''The White Queen'',<ref>{{Cite web|url=http://www.hollywoodreporter.com/live-feed/starz-white-queen-philippa-gregory-janet-mcteer-367753|title=Starz Orders Historical Drama Based on Philippa Gregory's 'Cousins of War' Book Trilogy|date=2012-04-09|publisher=Hollywood Reporter|accessdate=2012-09-07}}</ref> yang dibuat berdasarkan novel Philippa Gregory's ''The Cousins' War'' yang isinya tentang wanita dalam [[Perang Mawar|Wars of the Roses]].<ref>{{Cite web|url=http://www.bbc.co.uk/mediacentre/latestnews/2012/white-queen.html|title=Media Centre - The White Queen, a new ten-part drama for BBC One|date=2012-08-31|publisher=BBC|accessdate=2012-09-07}}</ref> Performa Ferguson dalam ''The White Queen'' has telah berhasil mendapat penghargaan,<ref>{{Cite web|url=http://www.elleuk.com/star-style/news/5-reasons-to-watch-the-white-queen|title=5 reasons to watch The White Queen|accessdate=27 July 2013}}</ref> yaitu nominasi sebagai Aktris Terbaik - Miniseri atau Film Televisi [[Penghargaan Golden Globe|Golden Globe]].
Pada tahun 2015, Ferguson bermain sebagai Ilsa Faust, pemeran utama wanita <ref>{{Cite news|url=http://time.com/3977847/rebecca-ferguson-mission-impossible-rogue-nation-tom-cruise/|title=Meet Rebecca Ferguson, the Scene-Stealing Star of Mission Impossible|date=30 July 2015|work=[[Time (magazine)|TIME]]|accessdate=1 August 2015}}</ref><ref>{{Cite news|url=http://www.nytimes.com/2015/08/02/fashion/after-mission-impossible-rebecca-fergusons-impossible-calm-amid-a-whirlwind-mission.html|title=After ‘Mission: Impossible,’ Rebecca Ferguson’s Impossible Calm Amid a Whirlwind Mission|date=31 July 2015|work=[[The New York Times]]|accessdate=1 August 2015}}</ref> dalam ''[[Mission: Impossible 5|Mission: Impossible – Rogue Nation]]'', dan mendapat banyak pujian.<ref>{{Cite web|url=http://www.deadline.com/2014/07/mission-impossible-5-female-lead-goes-to-rebecca-ferguson/|title='Mission: Impossible 5' Female Lead Goes To Rebecca Ferguson|last=Fleming|first=Mike|date=|publisher=Deadline.com|accessdate=2014-07-15}}</ref><ref>{{Cite news|url=http://www.ew.com/article/2015/07/31/mission-impossible-rogue-nation-rebecca-ferguson|title=Meet Rebecca Ferguson, the beautiful scene-stealer in Mission Impossible - Rogue Nation|date=31 July 2015|work=[[Entertainment Weekly]]|accessdate=1 August 2015}}</ref> Dia akan kembali bermain dalam film ''Mission: Impossible'' yang keenam.<ref>{{Cite web|url=http://www.showbiz411.com/2015/12/08/mission-accomplished-rebecca-ferguson-first-tom-cruise-leading-lady-doing-a-second-mi|title=Mission Accomplished: Rebecca Ferguson First Tom Cruise Leading Lady Doing a Second "M:I"|last=Friedman|first=Roger|date=December 8, 2015|publisher=Showbiz 411}}</ref>
