Templat:IndependentSpiritBestFemaleLead 2000–2020

l b s Penghargaan Independent Spirit untuk Aktris Pemimpin Terbaik (2000–2020)
Ellen Burstyn (2000) Sissy Spacek (2001) Julianne Moore (2002) Charlize Theron (2003) Catalina Sandino Moreno (2004) Felicity Huffman (2005) Shareeka Epps (2006) Ellen Page (2007) Melissa Leo (2008) Gabourey Sidibe (2009) Natalie Portman (2010) Michelle Williams (2011) Jennifer Lawrence (2012) Cate Blanchett (2013)
Daftar lengkap (1985–1999) (2000–2020)